Open AccessColchicine therapy in amyloidosis related with plasmacytic castleman disease presenting with nephrotic syndrome
Author(s) -
Saime Paydaş,
Semra Paydaş,
Melek Ergïn
Publication year - 2015
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.164589
Subject(s) - medicine , nephrotic syndrome , amyloidosis , castleman disease , colchicine , anemia , thrombocytosis , poems syndrome , pathology , disease , polyneuropathy , platelet
Castleman disease (CD) is a neoplasm that presents with single or multiple lymphadenopathy. The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy. In this paper, we report a young man with plasmacytic type CD and amyloid A (AA) deposition who presented with intra-abdominal mass and nephrotic syndrome. He was successfully treated with colchicine following surgery.