Open AccessOrthotropic liver transplantation for intractable neurological manifestations of Wilson′s disease
Author(s) -
Vaibhav Sutariya,
Anad H Tank,
Pranjal Modi
Publication year - 2015
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.157365
Subject(s) - medicine , fulminant hepatic failure , liver transplantation , wilson's disease , orthotopic liver transplantation , fulminant , cirrhosis , disease , liver disease , gastroenterology , transplantation , surgery
Wilson's disease (WD) is an inherited autosomal recessive disorder characterized by copper accumulation and toxicity, affecting mainly the liver and brain. Orthotopic liver transplantation (OLT) is the definitive therapy for patients with WD. Acute fulminant hepatic failure and decompensated cirrhosis are well-established indications for OLT. Patients with severe neurologic impairment can also be benefited by OLT. Here, we present a patient who underwent OLT for isolated neurological WD.