Open AccessEmphysematous pyelonephritis in a patient infected with the human immunodeficiency virus
Author(s) -
PA Mohamed Ashif,
Puvvada Sandeep,
Srivastava Pk
Publication year - 2012
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.100948
Subject(s) - medicine , obstructive uropathy , urinary system , proteus mirabilis , klebsiella pneumoniae , diabetes mellitus , human immunodeficiency virus (hiv) , coinfection , antibiotics , gastroenterology , immunology , escherichia coli , microbiology and biotechnology , pseudomonas aeruginosa , bacteria , biochemistry , chemistry , biology , gene , genetics , endocrinology
Emphysematous pyelonephritis (EPN) is a rapidly progressive and life-threatening infection that is seen most commonly in persons with diabetes. The infecting organisms usually consist of mixed flora, including Escherichia coli (68%), Klebsiella pneumoniae (9%) and Proteus mirabilis. Females are affected twice as often as men, and mortality rates can be as high as 80%. Obstructive uropathy, urinary calculi, calyceal stenosis and neoplasms are significant predisposing factors. We report a case of EPN in a patient with the human immunodeficiency virus infection, without diabetes mellitus or urinary tract obstruction, which responded remarkably to conservative management with antibiotics alone.