Chronological emergence of a class a carbapenemase-producing Enterobacter aerogenes in Taiwan | Zendy

TzongShi Chiueh | Zendy; ZhengYi Huang | Zendy; JunRen Sun | Zendy; Sheng-Ting Hsu | Zendy; Ching-Mei Yu | Zendy; CherngLih Perng | Zendy

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Chronological emergence of a class a carbapenemase-producing Enterobacter aerogenes in Taiwan

Author(s) -

TzongShi Chiueh,

ZhengYi Huang,

JunRen Sun,

Sheng-Ting Hsu,

Ching-Mei Yu,

CherngLih Perng

Publication year - 2014

Publication title -

journal of medical sciences

Language(s) - English

Resource type - Journals

eISSN - 2542-4939

pISSN - 1011-4564

DOI - 10.4103/1011-4564.129394

Subject(s) - enterobacter aerogenes , microbiology and biotechnology , enterobacter , biology , polymerase chain reaction , multiple drug resistance , gene , drug resistance , genetics , escherichia coli

This study reports the case of a 77-year-old, long-term, bedridden patient, with a nosocomial wound infection caused by a multidrug-resistant strain of Enterobacter aerogenes (E. aerogense). The isolate produced an Ambler-class A carbapenemase, which was demonstrated by the Modified Hodge test (MHT) and a confirmatory inhibition test. However, no known carbapenemase genes were discovered in this isolate by polymerase chain reactions (PCRs) with specific primers. New carbapenemase or other resistant mechanisms could be explored from the isolate of carbapenem-resistant E. aerogense, according to the revised criteria (CLSI, 2012)

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