Open AccessChronological emergence of a class a carbapenemase-producing Enterobacter aerogenes in Taiwan
Author(s) -
Zheng-Yi Huang,
JunRen Sun,
Sheng-Ting Hsu,
Ching-Mei Yu,
CherngLih Perng,
TzongShi Chiueh
Publication year - 2014
Publication title -
yīxué yánjiū zázhì/journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2542-4939
pISSN - 1011-4564
DOI - 10.4103/1011-4564.129394
Subject(s) - enterobacter aerogenes , microbiology and biotechnology , enterobacter , biology , polymerase chain reaction , multiple drug resistance , gene , drug resistance , genetics , escherichia coli
This study reports the case of a 77-year-old, long-term, bedridden patient, with a nosocomial wound infection caused by a multidrug-resistant strain of Enterobacter aerogenes (E. aerogense). The isolate produced an Ambler-class A carbapenemase, which was demonstrated by the Modified Hodge test (MHT) and a confirmatory inhibition test. However, no known carbapenemase genes were discovered in this isolate by polymerase chain reactions (PCRs) with specific primers. New carbapenemase or other resistant mechanisms could be explored from the isolate of carbapenem-resistant E. aerogense, according to the revised criteria (CLSI, 2012)