Open AccessUtility of cytokine, adhesion molecule and acute phase proteins in early diagnosis of neonatal sepsis
Author(s) -
Manal Abdel Fattah,
Al Fadhil A. Omer,
S Asaif,
Regina Manlulu,
Tarig Karar,
Anwar Ahmed,
Ahmad Aljada,
Ayman M. Saleh,
Shoeb Qureshi,
Amre Nasr
Publication year - 2017
Publication title -
journal of natural science, biology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 30
eISSN - 2229-7707
pISSN - 0976-9668
DOI - 10.4103/0976-9668.198362
Subject(s) - procalcitonin , sepsis , medicine , neonatal sepsis , blood culture , neonatal intensive care unit , gastroenterology , tumor necrosis factor alpha , pediatric intensive care unit , prospective cohort study , c reactive protein , acute phase protein , cytokine , pediatrics , inflammation , antibiotics , microbiology and biotechnology , biology
Neonatal infection, including bacterial sepsis, is a major health care issue with an annual global mortality in excess of one million lives. Therefore, this study aimed to evaluate the potential diagnostic value of C-reactive protein (CRP), E-selectin, procalcitonin (PCT), interleukins-6 (IL-6), and tumor necrosis factor-α (TNF-α) both independently and in combination for the diagnosis of neonatal sepsis in its earliest stages.