Open AccessMetachronous multifocal myxoid liposarcoma involving the gastrointestinal tract. Management and literature review
Author(s) -
Nikolaos S. Salemis,
Charalampos Seretis,
Fotios Seretis,
Charalampos Christofyllakis,
Georgios Karalis
Publication year - 2014
Publication title -
journal of natural science, biology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 30
eISSN - 2229-7707
pISSN - 0976-9668
DOI - 10.4103/0976-9668.127325
Subject(s) - liposarcoma , medicine , myxoid liposarcoma , soft tissue , soft tissue sarcoma , gastrointestinal tract , sarcoma , rare disease , radiology , disease , pathology
Multifocal soft tissue sarcoma is a rare clinical entity occurring in 1% of patients with extremity soft tissue sarcoma and in 4.5% of patients with liposarcoma. Multifocal disease may arise either synchronously or metachronously and has been associated with poor prognosis. Herein, we have described a rare case of metachronous multifocal myxoid liposarcoma involving the gastrointestinal tract that developed 14 months after the resection of a myxoid buttock liposarcoma. Diagnostic evaluation and management of the patient are discussed along with a review of the relevant literature. We conclude that multifocal myxoid liposarcoma is a rare clinical entity that usually represents metastatic disease with poor prognosis. A thorough imaging and careful physical examination are essential in the preoperative evaluation and postoperative follow-up of patients with myxoid extremity liposarcomas, as these tumors are known to have a tendency to spread toward extrapulmonary sites, frequently without pulmonary metastases.