Open AccessUpper gastrointestinal bleed in a post menopausal woman due to combination of high first dose aspirin and clopidogrel prescribed for acute coronary syndrome
Author(s) -
Vishal R Tandon,
Rubeena Maqbool,
Iram Kahkashan,
Rashmi Sharma,
Vijay Khajuria,
Zahid Gillani
Publication year - 2015
Publication title -
journal of mid-life health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 11
eISSN - 0976-7819
pISSN - 0976-7800
DOI - 10.4103/0976-7800.165595
Subject(s) - clopidogrel , medicine , bleed , aspirin , acute coronary syndrome , incidence (geometry) , proton pump inhibitor , upper gastrointestinal bleeding , gastroenterology , cardiology , surgery , endoscopy , myocardial infarction , physics , optics
Combination of aspirin, clopidogrel and enoxaparin remains the standard treatment for acute coronary syndrome (ACS) but is known to increase the incidence of upper gastrointestinal bleed (UGIB). We hereby report an unusual case of gastrointestinal bleed (GIB) as it resulted inspite of proton pump inhibitor (PPI) prophylaxis within the second day of treatment in a post-menopausal woman (PMW) with high first dose of aspirin clopidogrel dual combination in a patient of ACS.