Open AccessPostmenopausal choriocarcinoma: A rare case report
Author(s) -
Sunita Samal,
Setu Rathod,
Seetesh Ghose
Publication year - 2014
Publication title -
journal of mid-life health
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 11
eISSN - 0976-7819
pISSN - 0976-7800
DOI - 10.4103/0976-7800.141229
Subject(s) - choriocarcinoma , medicine , hysterectomy , trophoblast , abdominal hysterectomy , vaginal bleeding , gynecology , histopathology , menopause , postmenopausal bleeding , uterus , obstetrics , pregnancy , surgery , pathology , placenta , fetus , cancer , endometrial cancer , biology , genetics
Choriocarcinoma is a highly malignant epithelial tumor originating from trophoblast. It primarily occurs during the fertile period. Postmenopausal uterine choriocarcinoma is very rare. We present a case of choriocarcinoma in a postmenopausal lady developing 5 years after menopause. She presented with heavy postmenopausal bleeding along with passage of vesicles per vaginum. Serum beta-hCG was 96,484 mIU/ml. Emergency abdominal hysterectomy with bilateral salpingo-ooperectomy was done due to intractable bleeding following suction and evacuation. Histopathology revealed uterine choriocarcinoma. She was treated with EMACO regimen following which her beta-hCG returned to normal in five cycles. The patient is under regular follow-up and is doing well.