Open AccessEfficacy, safety and cost-effectiveness of insulin sensitizers as add-on therapy in metabolic syndrome in patients with secondary sulfonylurea failure: A comparative study
Author(s) -
Rajiv Mahajan,
Anita Gupta,
Rakesh Gupta,
Kapil Gupta
Publication year - 2010
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/0976-500x.72349
Subject(s) - medicine , metformin , pioglitazone , sulfonylurea , metabolic syndrome , insulin , blood pressure , insulin resistance , body mass index , diabetes mellitus , endocrinology , gastroenterology , type 2 diabetes
Prevalence of metabolic syndrome (MS) is ~25% and it is currently becoming prevalent in children also. India is estimated to have the maximum number of patients of MS in the world. As insulin resistance is an integral part of MS and the rate of secondary sulfonylurea failure (SSUF) is also high, the present study was planned to evaluate the effects of insulin sensitizers as add-on therapy in MS with SSUF.