
Role of cinnarizine and nifedipine on anticonvulsant effect of sodium valproate and carbamazepine in maximal electroshock and pentylenetetrazole model of seizures in mice
Author(s) -
Ranjana Brahmane,
Vikrant V Wanmali,
Swanand Pathak,
Kartik J Salwe
Publication year - 2010
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/0976-500x.72348
Subject(s) - cinnarizine , nifedipine , carbamazepine , pharmacology , anticonvulsant , medicine , sodium , epilepsy , anesthesia , chemistry , calcium , organic chemistry , psychiatry
To study the effect of calcium channel blockers (CCBs) cinnarizine and nifedipine on maximal electroshock (MES)-induced and pentylenetetrazole (PTZ)-induced convulsions and also their effect in combination with conventional antiepileptic drugs (CAED).