
Clozapine-induced cataract in a young female
Author(s) -
Alam Ms,
Praveen Kumar Kv
Publication year - 2016
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/0976-500x.195904
Subject(s) - clozapine , medicine , amiodarone , antipsychotic , cataract surgery , antipsychotic drug , chlorpromazine , adverse effect , drug , drug reaction , pediatrics , psychiatry , schizophrenia (object oriented programming) , pharmacology , ophthalmology , atrial fibrillation
A variety of systemic drugs including corticosteroids, amiodarone and antipsychotics have been known to cause cataract formation. Typical antipsychotics such as chlorpromazine have been reported to cause cataract formation in varying rates ranging from 22% to 80%. Cataract as an adverse effect resulting from the long term use of atypical antipsychotic has rarely been mentioned in literature, and there is only a single case report of cataract formation from prolonged use of clozapine. We report a rare case of clozpine induced cataract in a young female. The patient was advised to consult her psychiatrist for a change of drug and to undergo cataract surgery.