Open AccessType 1 neurofibromatosis with periodontal manifestations
Author(s) -
Pramod Kumar,
Akshay Dhobley,
Harshal Kumar,
Sandeep Jain
Publication year - 2016
Publication title -
indian journal of dental sciences
Language(s) - English
Resource type - Journals
eISSN - 2231-2293
pISSN - 0976-4003
DOI - 10.4103/0976-4003.191727
Subject(s) - neurofibromatosis , medicine , penetrance , neurofibromin 1 , disease , dermatology , neurofibromatosis type i , pathology , genetics , biology , gene , phenotype
Neurofibromatosis type 1 (NF1) also known as von Recklinghausen's disease is an autosomal dominant disease transmitted with a high degree of penetrance. The disease is expressed in different forms. NF1 accounts for almost 90% of the cases although nine types have been described to date. We report one such case of a 36-year-old female who presented with multiple nodules on the body. He was diagnosed to have NF1, having satisfied the diagnostic criteria for the same. Oral manifestations can be found in almost 72% of NF1 patients. This case report highlights the clinical features and diagnostic criteria of NF1, the prevalence and the significance of intraoral neurofibromas and the need for the dental practitioner to be aware of this condition