Open AccessPeripheral giant cell granuloma
Author(s) -
Padam Narayan Tandon,
Shruti Gupta,
Divender Gupta,
Sunit Kumar Jurel,
Abhishek Saraswat
Publication year - 2012
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.95121
Subject(s) - giant cell , pathology , lesion , periosteum , medicine , nodule (geology) , stromal cell , granuloma , biopsy , soft tissue , peripheral blood mononuclear cell , anatomy , biology , in vitro , paleontology , biochemistry
Peripheral giant cell granuloma or the so-called "giant cell epulis" is the most common oral giant cell lesion. It normally presents as a soft tissue purplish-red nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells. This lesion probably does not represent a true neoplasm, but rather may be reactive in nature, believed to be stimulated by local irritation or trauma, but the cause is not certainly known. This article reports a case of peripheral giant cell granuloma arising at the maxillary anterior region in a 22-year-old female patient. The lesion was completely excised to the periosteum level and there is no residual or recurrent swelling or bony defect apparent in the area of biopsy after a follow-up period of 6 months.