Open AccessMetastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation
Author(s) -
Satya Ranjan Misra,
Y Uday Shankar,
Varun Rastogi,
G Maragathavalli
Publication year - 2015
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.152966
Subject(s) - medicine , malignancy , pathognomonic , hepatocellular carcinoma , maxilla , metastasis , pathology , differential diagnosis , anaplasia , carcinoma , metastatic carcinoma , disease , radiology , cancer , anatomy
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.