Open AccessNormocalcemic hyperparathyroidism manifesting as brown tumor of mandible: A case report
Author(s) -
Dhanya S Rao,
Anupama N. Kalappanavar,
Rajeshwari G Annigeri
Publication year - 2016
Publication title -
journal of orofacial sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.171
H-Index - 6
eISSN - 2320-4737
pISSN - 0975-8844
DOI - 10.4103/0975-8844.181933
Subject(s) - medicine , primary hyperparathyroidism , hypophosphatemia , asymptomatic , brown tumor , mandible (arthropod mouthpart) , hyperparathyroidism , parathyroid hormone , osteitis fibrosa cystica , surgery , secondary hyperparathyroidism , calcium , botany , genus , biology
Patients with primary hyperparathyroidism (HPT) may be asymptomatic and clinical presentation of the tumor in the jaws can be the first sign of the disease. Only 2% of all primary HPT cases occur in patients below the age of 30 years. [1] Owing to the improved methods of blood analysis in the last two decades, most of the recent cases of primary HPT are diagnosed early and asymptomatically. [2] Most cases of primary HPT are identified by hypercalcemia and hypophosphatemia on routine multi-panel serum testing. [3] This makes advanced disease with brown tumor extremely rare these days, the mandible being affected only in 4% of the cases. [2] Here, we report a case of a 23-year-old female patient who presented with a swelling at body of mandible, with hypophosphatemia, increased parathyroid hormone, and normal serum calcium levels based on which a diagnosis of brown tumor was given