Open AccessNager′s acrofacial dysostosis
Author(s) -
Arpita Rai,
Kirty Nandimath,
Atul Sattur,
Venkatesh G Naikmasur
Publication year - 2013
Publication title -
journal of orofacial sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.171
H-Index - 6
eISSN - 2320-4737
pISSN - 0975-8844
DOI - 10.4103/0975-8844.124263
Subject(s) - dysostosis , anatomy , synostosis , hypoplasia , craniofacial , medicine , palpebral fissure , orthodontics , surgery , congenital disease , psychiatry
Acrofacial dysostosis (AFD) is a generic name for a variety of different but possibly related genetic disorders that result in craniofacial and limb malformations and are, therefore, categorized under oroacral disorders. Several different variants have been identified and Nager preaxial AFD represents the association of mandibulofacial dysostosis with limb anomalies, particularly hypoplasia of the radial aspect of the hand. This report features a case of a 21-year-old male presenting with malar hypoplasia, downward sloping palpebral fissures, high-arched palate, radioulnar synostosis, hypoplasia of the right thumb and lower limb anomalies