Open AccessImmunofluorescence and its application in dermatopathology with oral manifestations: Revisited
Author(s) -
RS Arvind Babu,
KLalith Prakash Chandra,
Pranatharthi H. Chandrasekar,
K U Goma Kumar,
BV Ramana Reddy,
G. Sridhar Reddy
Publication year - 2013
Publication title -
journal of orofacial sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.171
H-Index - 6
eISSN - 2320-4737
pISSN - 0975-8844
DOI - 10.4103/0975-8844.113680
Subject(s) - dermatopathology , immunofluorescence , pathology , direct fluorescent antibody , medicine , histopathology , gold standard (test) , immune system , dermatology , antibody , immunology
The use of fluorescence probes the field of cell and molecular biology. Immunofluorescence is a molecular method for detection of antigen or antibody in a tissue section/serum sample. Although histopathology remains gold standard for most of auto immune, immune mediated and vesiculo - bullous diseases. Immunofluorescence is an ancillary investigation, which are used to support clinical diagnosis more evidently. This method provides additional diagnostic, prognostic information and remains more specific diagnostic aid for vesiculo - bullous diseases of skin. This review article discusses about immunofluorescence techniques and its application in dermatopathology with oral manifestations