Open AccessA novel chiral GC/MS method for the analysis of fluoxetine and norfluoxetine enantiomers in biological fluids
Author(s) -
Janet Mifsud,
Lino Sghendo
Publication year - 2012
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.99065
Subject(s) - enantiomer , chromatography , chemistry , selected ion monitoring , gas chromatography–mass spectrometry , fluoxetine , gas chromatography , mass spectrometry , pharmacokinetics , stereochemistry , pharmacology , medicine , biochemistry , receptor , serotonin
A novel robust chiral gas chromatographic/mass spectrometric (GC/MS) method for the separation and measurement of fluoxetine and norfluoxetine enantiomers in urine and plasma was developed.