Open AccessFormulation and evaluation of rifampicin sustained release tablets using juice of Citrus limetta as bio-retardant
Author(s) -
KPawan Gaur,
Kulwant Soam,
SK Gupta,
Prashant Dabral
Publication year - 2012
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.94126
Subject(s) - biopolymer , fire retardant , natural polymers , biocompatible material , polymer , controlled release , biodegradable polymer , chemistry , materials science , biomedical engineering , medicine , nanotechnology , organic chemistry
The advantages of biopolymers over synthetic polymers are low cost, natural origin, free from side effects, biocompatible, bio-acceptable, environmental friendly processing, local availability, better patient tolerance as well as public acceptance. Sustained release tablets containing rifampicin was prepared by adding 100 mg polymer and 50 mg Drug and Granules. Same procedure was followed with 3% and 5% of polymer for preparation of sustained release tablets. Additional Tablets of 100 mg, 200 mg and 400 mg were prepared using 5% of the polymer. The results indicated that the selected biopolymer had a good release retardant property thus it can be concluded that the selected biopolymer can be utilized as low cost natural biocompatible and biodegradable agent.