Inhibitor designing, virtual screening, and docking studies for methyltransferase: A potential target against dengue virus
Author(s) -
Aakash Deep,
Jagbir Singh,
Mahesh Kumar,
Rani Mansuri,
GaneshChandra Sahoo
Publication year - 2015
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.171682
Subject(s) - virtual screening , dengue virus , docking (animal) , dengue fever , methyltransferase , drug discovery , computational biology , drug , virus , virology , pharmacology , chemistry , methylation , biology , medicine , biochemistry , nursing , gene
Aim of this work was to design and identify some S-adenosyl-L-homocysteine (SAH) analogs as inhibitors of S-adenosyl-L-methionine-dependent methyltransferase (MTase) protein using computational approaches.
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