Open AccessInhibitor designing, virtual screening, and docking studies for methyltransferase: A potential target against dengue virus
Author(s) -
Jagbir Singh,
Mahesh Kumar,
Rani Mansuri,
Ganesh Chandra Sahoo,
Aakash Deep
Publication year - 2016
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.171682
Subject(s) - virtual screening , dengue virus , docking (animal) , dengue fever , methyltransferase , drug discovery , computational biology , drug , virus , virology , pharmacology , chemistry , methylation , biology , medicine , biochemistry , nursing , gene
Aim of this work was to design and identify some S-adenosyl-L-homocysteine (SAH) analogs as inhibitors of S-adenosyl-L-methionine-dependent methyltransferase (MTase) protein using computational approaches.