Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation | Zendy

Raghuvir R. S. Pissurlenkar | Zendy; M. Nagarsenker | Zendy; D. M. Bramhane | Zendy; P. R. Kulkarni | Zendy; Elvis A. F. Martis | Zendy; Evans C. Coutinho | Zendy

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Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation

Author(s) -

Raghuvir R. S. Pissurlenkar,

M. Nagarsenker,

D. M. Bramhane,

P. R. Kulkarni,

Elvis A. F. Martis,

Evans C. Coutinho

Publication year - 2015

Publication title -

journal of pharmacy and bioallied sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 36

eISSN - 0976-4879

pISSN - 0975-7406

DOI - 10.4103/0975-7406.171680

Subject(s) - pioglitazone , in vivo , cyclodextrin , characterization (materials science) , chemistry , pharmacology , combinatorial chemistry , computational biology , medicine , biochemistry , nanotechnology , materials science , endocrinology , biology , microbiology and biotechnology , diabetes mellitus , type 2 diabetes

The objective of present study was to study the influence of different β-cyclodextrin derivatives and different methods of complexation on aqueous solubility and consequent translation in in vivo performance of Pioglitazone (PE).

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