Open AccessSynthesis, characterization and in silico biological activity of some 2-(N,N-dimethyl guanidinyl)-4,6-diaryl pyrimidines
Author(s) -
Rajasekhar Komarla Kumarachari,
Sivakumar Peta,
Abdrrahman Shemsu Surur,
Yenus Tadesse Mekonnen
Publication year - 2016
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.171678
Subject(s) - in silico , characterization (materials science) , chemistry , combinatorial chemistry , computational biology , biology , biochemistry , nanotechnology , materials science , gene
As pyrimidine is a basic nucleus in DNA and RNA, it has been found to be associated with diverse biological activities. Pyrimidine derivatives were reported to possess anticonvulsant, antimicrobial, anti-inflammatory, antitumor, and antihistaminic. Recently, our team reported the anti-inflammatory and antimicrobial evaluation of some pyrimidines.