Hepatoprotective potential of kumaryasava and its concentrate against CCl4-induced hepatic toxicity in Wistar rats | Zendy

Sayeed Ahmad | Zendy; Mohammad Ahmed Khan | Zendy; Arun Kumar Gupta | Zendy; J.L.N. Sastry | Zendy

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Hepatoprotective potential of kumaryasava and its concentrate against CCl4-induced hepatic toxicity in Wistar rats

Author(s) -

Sayeed Ahmad,

Mohammad Ahmed Khan,

Arun Kumar Gupta,

J.L.N. Sastry

Publication year - 2015

Publication title -

journal of pharmacy and bioallied sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 36

eISSN - 0976-4879

pISSN - 0975-7406

DOI - 10.4103/0975-7406.168029

Subject(s) - ccl4 , toxicity , pharmacology , liver toxicity , medicine , traditional medicine , chemistry , carbon tetrachloride , organic chemistry

Kumaryasava (KS) is a marketed Ayurvedic formulation containing Aloe vera as the main ingredient. It has been used widely for the treatment of liver disorders; however, there is a lack of modern scientific data on hepatoprotection. The recommended dose of KS is high and up to 60 mL/day. The present study describes the preparation of new KS concentrate and evaluation of comparative hepatoprotective activity of KS and prepared KS concentrate at one-third of KS dose against CCl4-induced hepatic toxicity.

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