Open AccessHepatoprotective potential of kumaryasava and its concentrate against CCl4-induced hepatic toxicity in Wistar rats
Author(s) -
Mohammad Ahmed Khan,
Arun Kumar Gupta,
J. L. N. Sastry,
Sayeed Ahmad
Publication year - 2015
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.168029
Subject(s) - ccl4 , toxicity , pharmacology , liver toxicity , medicine , traditional medicine , chemistry , carbon tetrachloride , organic chemistry
Kumaryasava (KS) is a marketed Ayurvedic formulation containing Aloe vera as the main ingredient. It has been used widely for the treatment of liver disorders; however, there is a lack of modern scientific data on hepatoprotection. The recommended dose of KS is high and up to 60 mL/day. The present study describes the preparation of new KS concentrate and evaluation of comparative hepatoprotective activity of KS and prepared KS concentrate at one-third of KS dose against CCl4-induced hepatic toxicity.