A high performance thin layer chromatographic method for the estimation of colchicine in different formulations | Zendy

Sayeed Ahmad | Zendy; M. Fahim | Zendy; Mhaveer Singh | Zendy; YT Kamal | Zendy; Hayat M. Mukhtar | Zendy

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A high performance thin layer chromatographic method for the estimation of colchicine in different formulations

Author(s) -

Sayeed Ahmad,

M. Fahim,

Mhaveer Singh,

YT Kamal,

Hayat M. Mukhtar

Publication year - 2015

Publication title -

journal of pharmacy and bioallied sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.268

H-Index - 36

eISSN - 0976-4879

pISSN - 0975-7406

DOI - 10.4103/0975-7406.168021

Subject(s) - chromatography , colchicine , detection limit , high performance thin layer chromatography , silica gel , chemistry , thin layer chromatography , medicine

Colchicine is a main alkaloid present in bitter and sweet variety of colchicum (Colchicum luteum Baker), which have been reported to possess anti-rheumatic, anti-gout, and anticancer potential. Colchicum is an important ingredient of several Unani and Herbal formulations. Quantification of colchicine will play a great role in quality control of these formulations. Hence, a high-performance thin layer chromatographic (TLC) method has been developed for the analysis of colchicine in Unani formulations of various dosage forms such as hubb (tablet) and capsules.

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