Open AccessCombinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats
Author(s) -
Songjukta Chakraborty,
Mukta Pujani,
Syed Ehtaishamul Haque
Publication year - 2015
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.160037
Subject(s) - atorvastatin , resveratrol , cardiac hypertrophy , medicine , cardiology , pharmacology , myocardial hypertrophy , muscle hypertrophy
Resveratrol is a natural polyphenol present mainly in grapes. It has been shown to offer strong cardio protection in animal models due to its ability to correct lipid peroxidation and maintain antioxidants level. Atorvastatin, a HMG-CoA reductase inhibitor, lowers cholesterol level and is commonly prescribed to heart patients. Our aim in this study was to see the combination effect of these two drugs against Isoproterenol-induced cardiac hypertrophy in rats.