Open AccessApoptosis in immune-mediated diseases
Author(s) -
S. Leena Sankari,
N. Aravindha Babu,
E. Rajesh,
Magesh Kasthuri
Publication year - 2015
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.155902
Subject(s) - apoptosis , pathogenesis , immune system , dysfunctional family , pathological , disease , immune dysregulation , immunology , medicine , bioinformatics , biology , cancer research , pathology , genetics , clinical psychology
Apoptosis plays a significant role in both the physiological and pathological process. A dysfunctional apoptotic system can lead to either excessive removal or prolonged survival of cells. Therefore, dysregulation is involved in the pathogenesis of a variety of immunological diseases. The present review aims to provide an overview regarding role of apoptosis in immune-mediated disease.