Open Access3D-QSAR study of benzotriazol-1-yl carboxamide scaffold as monoacylglycerol lipase inhibitors
Author(s) -
Obaid Afzal,
Suresh Kumar,
Rajiv Kumar,
Manu Jaggi,
Sandhya Bawa
Publication year - 2014
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.142957
Subject(s) - monoacylglycerol lipase , pharmacophore , quantitative structure–activity relationship , chemistry , lipase , stereochemistry , enzyme , biochemistry , endocannabinoid system , receptor
The purpose of this study is to build up the 3D pharmacophore of Monoacylglycerol lipase (MAGL) inhibitor and to provide the basis to design the novel and potent MAGL inhibitors.