Open AccessMitigation of starch-induced postprandial glycemic spikes in rats by antioxidants-rich extract of Cicer arietinum Linn. seeds and sprouts
Author(s) -
Ashok Kumar Tiwari,
Chinthapatla Sahana,
Amtul Zehra,
Madhusudana Kuncha,
Dharmesh Kumar,
Sachin B. Agawane
Publication year - 2013
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.120077
Subject(s) - postprandial , glycation , antioxidant , glycemic , vigna , oxidative stress , food science , diabetes mellitus , chemistry , radiata , starch , biochemistry , traditional medicine , biology , endocrinology , botany , medicine
Consumption of highly processed calories dense diet leads abrupt increase in postprandial blood glucose level, which in turn induces immediate oxidative stress. Postprandial hyperglycemia (PPHG) and resultant oxidative stress is one of the earliest detectable abnormalities in diabetes prone individuals, independent risk factor for development of cardiovascular disorders (CVD), a major pathophysiological link between diabetes and CVD and an important contributing factor in atherogenesis even in non-diabetic individuals. Therefore, dietary supplements mitigating PPHG spikes along with potent antioxidant activities may help decrease development of PPHG and oxidative stress induced pathogenesis.