Open AccessQuantitative determination of imatinib stability under various stress conditions
Author(s) -
Khalid M. Alkharfy,
Rao Muzaffar A. Khan,
Majed Al-Asmari,
Baderelddin Hashim Alhadeyah,
Ajaz Ahmad
Publication year - 2013
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.106570
Subject(s) - chromatography , high performance liquid chromatography , imatinib , chemistry , acetonitrile , forced degradation , degradation (telecommunications) , imatinib mesylate , correlation coefficient , analytical chemistry (journal) , reversed phase chromatography , medicine , telecommunications , statistics , mathematics , myeloid leukemia , computer science , immunology
A simple, rapid, reverse phase and stability-indicating high-performance liquid chromatography (HPLC) method for the estimation of imatinib in solution and in plasma under forced degradation conditions was developed.