Open AccessTriple antibiotic paste in root canal therapy
Author(s) -
Rangasamy Vijayaraghavan,
V Mahesh Mathian,
Alagappan Meenakshi Sundaram,
Ramachandran Karunakaran,
Selvaraj Vinodh
Publication year - 2012
Publication title -
journal of pharmacy and bioallied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 36
eISSN - 0976-4879
pISSN - 0975-7406
DOI - 10.4103/0975-7406.100214
Subject(s) - root canal , endodontic therapy , dentistry , medicine , minocycline , metronidazole , sterilization (economics) , antibiotics , biology , microbiology and biotechnology , monetary economics , foreign exchange , economics , foreign exchange market
The success of the endodontic treatment depends on the microbial suppression in the root canal and periapical region. Endodontic instrumentation alone cannot achieve a sterile condition. With the advent of non-instrumentation endodontic treatment and lesion sterilization and tissue repair, local application of antibiotics has been investigated. Triple antibiotic paste (TAP) containing metronidazole, ciprofloxacin, and minocycline has been reported to be a successful regimen in controlling the root canal pathogen and in managing non-vital young permanent tooth. This paper reviews the existing literature on biocompatibility, efficiency, drawbacks of TAP in endodontic therapy and pulp revascularization.