Open AccessThe newer aspect of dexmedetomidine use in dentistry: As an additive to local anesthesia, initial experience, and review of literature
Author(s) -
Pankaj Kumar,
Manju Thepra,
Amrish Bhagol,
Kannu Priya,
Virendra Singh
Publication year - 2016
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/0975-5950.196137
Subject(s) - dexmedetomidine , medicine , onset of action , local anesthetic , anesthesia , local anesthesia , potency , lidocaine , anesthetic , sedation , biochemistry , chemistry , in vitro
Despite the availability of a wide variety of pharmacological agents in the field of anesthesia, there has always been a continuous search for newer local anesthetic agents with improved efficacy, potency, and better handling properties. Dexmedetomidine, a selective alpha-2 adrenergic receptor agonist, is an emerging agent for provision of additive local anesthetic effect if used with conventional local anesthetics, which can be implicated in dentistry for performing many minor oral surgical procedures. The present paper reports a pilot study comparing clinical efficacy and potency of this newer emerging drug in combination with lignocaine.