Open AccessEpithelial-myoepithelial carcinoma of floor of mouth: A case report with cytological, histological and immunohistochemical correlation
Author(s) -
Sujata Mohanty,
Himani Pathak
Publication year - 2014
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/0975-5950.154835
Subject(s) - medicine , myoepithelial cell , pathology , adenoid cystic carcinoma , pleomorphic adenoma , malignancy , carcinoma , floor of mouth , lesion , immunohistochemistry , mixed tumor , salivary gland , anatomy , tongue
A 61-year-old female presented with a 3-year-old swelling in the right floor of mouth. Clinical examination and fine needle aspiration cytology suggested a benign lesion. The mass was excised locally along with the involved sublingual and deep part of submandibular gland and duct. Post-operative histopathological examination revealed features of pleomorphic adenoma. However, on revision of histological sections, features were predominantly of a rare malignancy of the salivary glands, epithelial-myoepithelial carcinoma (EMC), along with focal areas of adenoid cystic carcinoma (Ad CC). The tumor was p-63, s-100 and smooth muscle actin positive but C-kit was negative, which ruled out Ad CC and the possibility of a hybrid carcinoma. The aim of this article is to describe a rare case of EMC in the floor of mouth and the confusing cytological picture that it created.