Open AccessTurmeric - A new treatment option for lichen planus: A pilot study
Author(s) -
Vibha Singh,
Mahesh Pal,
Shalini Gupta,
Shrikant Tiwari,
Laxman R Malkunje,
Sankha Subhra Das
Publication year - 2013
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/0975-5950.127651
Subject(s) - medicine , curcumin , pathogenesis , immunology , antigen , immune system , rhizome , traditional medicine , oral lichen planus , immunity , pharmacology
Turmeric is dried rhizome of the perennial herbs curcumalonga. It is called Haldi in Hindi, turmeric in English, ukon in Japanese. It has been used in Asian Medicine since the second millennium BC. It's utility is referred to in the ancient Hindu script the Ayurveda. Pathogenesis of the OLP should be taken in consideration for the treatment point of view. The Cell mediated immunity to secondary antigenic change in oral mucous membrane is thought to play a major role in its pathogenesis modified keratocyte surface antigens are the primary target for cytotoxic cellular response. Curcumin also been shown to have immune modulatory effect involving activation of host macrophages and natural killer cells and modulation of lymphocytes mediated function.