Open AccessDengue: A rare differential of acute hepatic failure
Author(s) -
Shahzad Alam,
Akhilesh Kumar Singh,
Balvir Singh,
Ayush Agarwal
Publication year - 2015
Publication title -
medical journal of dr. d y patil university/medical journal of dr. d.y. patil university
Language(s) - English
Resource type - Journals
eISSN - 2278-7119
pISSN - 0975-2870
DOI - 10.4103/0975-2870.169931
Subject(s) - dengue fever , medicine , myalgia , chills , coagulopathy , fulminant hepatic failure , hepatic encephalopathy , emergency department , encephalopathy , disseminated intravascular coagulation , differential diagnosis , liver function tests , shock (circulatory) , pediatrics , intensive care medicine , cirrhosis , immunology , pathology , liver transplantation , psychiatry , transplantation
Dengue is viral illness which manifests as high grade fever, myalgia, hemorrhagic manifestation and shock. Recently, dengue has been reported with rare presentations like encephalopathy, liver failure, and renal failure. We are presenting a case of acute fulminant liver failure due to dengue in which a 19-year-old previously healthy female who presented to us in the emergency department with complaints of high grade fever for past 3 days without chills and rigors, and altered sensorium past 1 day. The patient had icterus. On laboratory evaluation, her liver function tests were deranged while neuroimaging was normal. In view of presence of coagulopathy and altered sensorium, a diagnosis of dengue related acute hepatic failure was made. The patient was provided supportive and symptomatic management to which she responded and was discharged a few days later and is on regular follow-up