Open AccessBlack pancreatic neuro-endocrine tumor: A rare finding
Author(s) -
Shailja Puri Wahal,
NK Mohindroo,
Shobla Mohindroo
Publication year - 2015
Publication title -
medical journal of dr. d y patil university/medical journal of dr. d.y. patil university
Language(s) - English
Resource type - Journals
eISSN - 2278-7119
pISSN - 0975-2870
DOI - 10.4103/0975-2870.164951
Subject(s) - neuromelanin , melanin , endocrine system , pathology , lipofuscin , pancreas , biology , medicine , endocrinology , hormone , substantia nigra , parkinson's disease , disease , genetics
Pigmented lesions most commonly encountered in any organ are due to deposition of melanin in primary or metastatic malignant melanoma. Other less common pigments are lipofuscin and neuromelanin. Lipofuscin and neuromelanin are usually associated with benign lesions. Differentiating melanin from lipofuscin and neuromelanin is important as the former is usually associated with malignancy. However, melanin can occur in benign lesion also. All there pigments are differentiated by histopathological examination, histochemical stain, and immunohistochemistry. Black pigment is associated with black adenoma of the adrenal gland, neuro-endocrine tumor of lung, and foregut; however, it is rarely seen in neuro-endocrine tumor of the pancreas. We report a case of 61-year-old male patient with neuro-endocrine tumor of the pancreas associated with extensive deposition of black-colored melanin pigment