Open AccessParaquat: A fatal poison
Author(s) -
J Shashibhushan,
K Venugopal,
Mudegoudara Lingaraja,
CP Patanjali,
C Suresh,
Huggi Vishwanath
Publication year - 2015
Publication title -
medical journal of dr. d y patil university/medical journal of dr. d.y. patil university
Language(s) - English
Resource type - Journals
eISSN - 2278-7119
pISSN - 0975-2870
DOI - 10.4103/0975-2870.157090
Subject(s) - paraquat , antidote , medicine , intensive care medicine , respiratory failure , respiratory distress , acute respiratory distress , cause of death , toxicity , surgery , lung , biology , biochemistry , disease
Paraquat (1, 1′-dimethyl-4, 4′-dipyridylium) is a bipyridilium herbicide used widely in our country and is a highly toxic compound. This compound is very notorious to cause rapid development of renal, liver, and respiratory failure with very high mortality due to lack of specific antidote and dearth of high-quality evidence-based treatment. Respiratory system involvement is the most common cause of death in these people. We hereby report a fatal case of a 30-year-old male with a history of paraquat consumption. The patient developed oliguric renal failure, deterioration of liver function, and acute respiratory distress syndrome over next few days. Different treatment modalities were tried to manage patient′s condition. In this case, none of the strategies worked well, and death ensued due to multi-organ dysfunction syndrome