Open AccessOlanzapine induced tardive dyskinesia
Author(s) -
Rudraprosad Chakraborty,
Aroni Chatterjee,
Suprakash Chaudhury
Publication year - 2014
Publication title -
medical journal of dr. d y patil university/medical journal of dr. d.y. patil university
Language(s) - English
Resource type - Journals
eISSN - 2278-7119
pISSN - 0975-2870
DOI - 10.4103/0975-2870.122790
Subject(s) - olanzapine , tardive dyskinesia , clozapine , medicine , dyskinesia , anesthesia , schizophrenia (object oriented programming) , psychiatry , parkinson's disease , disease
Olanzapine is considered to have significantly less risk of tardive dyskinesia (TD) compared to first generation antipsychotics. We describe two patients who developed TD after prolonged use of olanzapine. Both the patients received no medications prior to the treatment with olanzapine. They neither received any other medication along with olanzapine nor any injectible antipsychotics. In one patient, TD improved completely after withdrawal of olanzapine and treatment with clozapine, but recurred after a retrial of olanzapine. In the other patient, reduction of dose of olanzapine was tried without any success. Despite a substantially lower risk than first generation antipsychotics, TD is not entirely absent with olanzapine