Open AccessGamma-irradiated sterile cornea for use in corneal transplants in a rabbit model
Author(s) -
Junko Yoshida,
Thomas Heflin,
Andrea Zambrano,
Qing Pan,
Huan Meng,
Jiangxia Wang,
Walter J. Stark,
Yassine J. Daoud
Publication year - 2015
Publication title -
middle east african journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.357
H-Index - 25
eISSN - 0975-1599
pISSN - 0974-9233
DOI - 10.4103/0974-9233.159760
Subject(s) - cornea , ophthalmology , medicine , cryopreservation , endothelium , corneal endothelium , edema , anatomy , surgery , biology , embryo , endocrinology , microbiology and biotechnology
Gamma irradiated corneas in which the donor keratocytes and endothelial cells are eliminated are effective as corneal lamellar and glaucoma patch grafts. In addition, gamma irradiation causes collagen cross inking, which stiffens collagen fibrils. This study evaluated gamma irradiated corneas for use in corneal transplantations in a rabbit model comparing graft clarity, corneal neovascularization, and edema.