Acute bilateral endophthalmitis following bilateral intravitreal bevacizumab (avastin) injection | Zendy

Alireza Khodabande | Zendy; Ali Tabatabaii | Zendy; Aliasghar Ahmadraji | Zendy; Mohammadreza Mansouri | Zendy

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Acute bilateral endophthalmitis following bilateral intravitreal bevacizumab (avastin) injection

Author(s) -

Alireza Khodabande,

Ali Tabatabaii,

Aliasghar Ahmadraji,

Mohammadreza Mansouri

Publication year - 2013

Publication title -

middle east african journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.357

H-Index - 25

eISSN - 0975-1599

pISSN - 0974-9233

DOI - 10.4103/0974-9233.106402

Subject(s) - medicine , endophthalmitis , bevacizumab , ophthalmology , surgery , chemotherapy

The clinical presentation and management of two patients who presented with acute bilateral endophthalmitis following bilateral intravitreal bevacizumab injection. Both cases were diagnosed clinically and subsequent to a vitreous sample, intravitreal ceftazidime (2.25 mg/0.1 ml) and vancomycin (1 mg/0.1 ml) were injected. One patient had a significant improvement in signs and symptoms after intravitreal antibiotics. However, there were was no improvement in the other patient and pars plana vitrectomy was performed bilaterally. Vitreous cultures were positive in both cases for Staphylococcus epidermidis.

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