Open AccessAcute bilateral endophthalmitis following bilateral intravitreal bevacizumab (avastin) injection
Author(s) -
Ali Tabatabaii,
Aliasghar Ahmadraji,
Alireza Khodabande,
M R Mansouri
Publication year - 2013
Publication title -
middle east african journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.357
H-Index - 25
eISSN - 0975-1599
pISSN - 0974-9233
DOI - 10.4103/0974-9233.106402
Subject(s) - medicine , vitrectomy , endophthalmitis , pars plana , ceftazidime , bevacizumab , vancomycin , ophthalmology , staphylococcus epidermidis , surgery , visual acuity , staphylococcus aureus , chemotherapy , pseudomonas aeruginosa , genetics , biology , bacteria
The clinical presentation and management of two patients who presented with acute bilateral endophthalmitis following bilateral intravitreal bevacizumab injection. Both cases were diagnosed clinically and subsequent to a vitreous sample, intravitreal ceftazidime (2.25 mg/0.1 ml) and vancomycin (1 mg/0.1 ml) were injected. One patient had a significant improvement in signs and symptoms after intravitreal antibiotics. However, there were was no improvement in the other patient and pars plana vitrectomy was performed bilaterally. Vitreous cultures were positive in both cases for Staphylococcus epidermidis.