Open AccessMicrosporidial spores can cross the intact descemet membrane in deep stromal infection
Author(s) -
Somasheila I Murthy,
Vishram A Sangit,
Varsha M Rathi,
Geeta K. Vemuganti
Publication year - 2013
Publication title -
middle east african journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.357
H-Index - 25
eISSN - 0975-1599
pISSN - 0974-9233
DOI - 10.4103/0974-9233.106399
Subject(s) - medicine , stroma , histopathology , stromal cell , descemet membrane , keratitis , pathology , spore , ophthalmology , cornea , biology , microbiology and biotechnology , immunohistochemistry
We report a rare case of a deep stromal keratitis with a chronic indolent course, diagnosed as microsporidial keratitis from corneal scrapings. The patient's condition worsened despite medical therapy and penetrating keratoplasty was performed. The histopathology of the corneal tissue revealed multiple microsporidial spores in the posterior stroma and the endothelial exudates, whereas there was no clinical or histopathological breach in Descemet's membrane. This is the second report in the literature to report that micropsoridial spores can cross the intact Descemet's membrane.