Open AccessIn vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
Author(s) -
Nayan R Bhalodia,
Pankaj Nariya,
Rabinarayan Acharya,
Vinay J Shukla
Publication year - 2012
Publication title -
ayu
Language(s) - English
Resource type - Journals
eISSN - 0976-9382
pISSN - 0974-8520
DOI - 10.4103/0974-8520.100329
Subject(s) - antimicrobial , cassia , microbiology and biotechnology , antibacterial activity , staphylococcus aureus , candida albicans , aspergillus flavus , bacteria , pathogenic bacteria , aspergillus niger , traditional medicine , pseudomonas aeruginosa , biology , chemistry , food science , medicine , genetics , alternative medicine , pathology , traditional chinese medicine
Aim of the study is to assess the antimicrobial activity Cassia fistula fruit pulp extracts on some bacterial and fungal strains. Hydro alcohol and chloroform extracts of Cassia fistula fruit pulp were evaluated for the potential antimicrobial activity. The antimicrobial activity was determined in both the extracts using the agar disc diffusion method. Extracts were effective on tested microorganisms. The antibacterial and antifungal activities of solvent extracts (5, 25, 50, 100, 250 μg/mL) of C. fistula were tested against two gram positive, two gram negative human pathogenic bacteria and three fungi, respectively. Crude extracts of C. fistula exhibited moderate to strong activity against most of the bacteria tested. The tested bacterial strains were Staphylococcus aureus, Streptococcus pyogenes, Escherichia coil, Pseudomonas aeruginosa, and fungal strains were Aspergillus. niger, Aspergillus. clavatus, Candida albicans. The antibacterial potential of the extracts were found to be dose dependent. The antibacterial activities of the C. fistula were due to the presence of various secondary metabolites. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.