Possible implication of oxidative stress in anti filarial effect of certain traditionally used medicinal plants in vitro against Brugia malayi microfilariae | Zendy

Komal Goswami | Zendy; MV.R Reddy | Zendy; RD Sharma | Zendy; AR Veerpathran | Zendy; Gajalakshmi Dakshinamoorthy | Zendy; KN Sahare | Zendy

Open Access

Possible implication of oxidative stress in anti filarial effect of certain traditionally used medicinal plants in vitro against Brugia malayi microfilariae

Author(s) -

Komal Goswami,

MV.R Reddy,

RD Sharma,

AR Veerpathran,

Gajalakshmi Dakshinamoorthy,

KN Sahare

Publication year - 2010

Publication title -

pharmacognosy research

Language(s) - English

Resource type - Journals

eISSN - 0976-4836

pISSN - 0974-8490

DOI - 10.4103/0974-8490.75453

Subject(s) - ricinus , traditional medicine , oxidative stress , lipid peroxidation , polyphenol , medicinal plants , biology , antioxidant , botany , chemistry , pharmacology , biochemistry , medicine

Tropical disease research scheme of World Health Organization has duly recognized traditional medicine as alternative for antifilarial drug development. Polyphenolic compounds present in traditionally used herbal medicines are natural antioxidants; however, paradoxically they may exert pro-oxidant effect. Popular drug diethyl carbamazine citrate harnesses the innate inflammatory response and the consequent oxidative assault to combat invading microbes.

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