Open AccessChromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil
Author(s) -
D. J. Taur,
Vijaya Kulkarni,
Ravindra Patil
Publication year - 2010
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/0974-8490.65504
Subject(s) - anthelmintic , eucalyptus globulus , albendazole , pharmacognosy , traditional medicine , eucalyptus oil , veterinary medicine , biology , helminths , eucalyptus , medicine , botany , ecology , immunology , biological activity , in vitro , biochemistry
In world Helminthes infections are the most widespread of all the infections in humans. The morbidity due to parasitic diseases has been increasing in our population. The gastrointestinal helminthes become resistant to the currently available anthelmintic drugs. Anthelmintic substances having considerable toxicity to human beings are present in foods derived from livestock, posing a serious threat to human health. Due to this, there is a need to derive new chemical substances from natural sources, for helminthes control. In this study, volatile oil isolated from Eucalyptus globulus Labill was evaluated for its anthelmintic activity on adult Indian earthworms, Pheretima posthuma, which have anatomical and physiological resemblance with the intestinal roundworm parasites of human beings. In concentrations of 0.05, 0.01 and 0.15 ml/ml, respectively, all the oil samples showed potent anthelmintic activity as compared to that of the standard drug albendazole at a concentration of 10 mg/ml.