Open AccessEvaluation of antiviral activity of essential oil of Trachyspermum Ammi against Japanese encephalitis virus
Author(s) -
Soumen Roy,
Pratibha Chaurvedi,
Abhay Chowdhary
Publication year - 2015
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/0974-8490.157977
Subject(s) - japanese encephalitis , virology , titer , virus , traditional medicine , mtt assay , vero cell , plaque reduction neutralization test , essential oil , in vivo , in vitro , encephalitis , medicine , chemistry , pharmacology , biology , chromatography , microbiology and biotechnology , biochemistry
Japanese encephalitis is a leading form of viral encephalitis, prevalent mostly in South Eastern Asia caused by Japanese encephalitis virus (JEV). It is transmitted by the mosquitoes of the Culex sp. The disease affects children and results in 50% result in permanent neuropsychiatric disorder. There arises a need to develop a safe, affordable, and potent anti-viral agent against JEV. This study aimed to assess the antiviral activity of ajwain (Trachyspermum ammi: Umbellifereae) essential oil against JEV.