Open AccessScreening of the antidepressant-like effect of the traditional Chinese medicinal formula Si-Ni-San and their possible mechanism of action in mice
Author(s) -
Long Yi,
Jing Li,
Binbin Liu,
Cheng-Fu Li
Publication year - 2013
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/0974-8490.105647
Subject(s) - behavioural despair test , tail suspension test , antidepressant , neurochemical , pharmacology , medicine , traditional chinese medicine , neurotrophic factors , mechanism of action , nerve growth factor , serotonin , traditional medicine , chemistry , endocrinology , hippocampus , in vitro , biochemistry , receptor , alternative medicine , pathology
The traditional Chinese medicine formula Si-Ni-San has well therapeutic applications in improvement of mental diseases including depression. However, the neuropharmacological and neuroendocrine mechanisms of the formula on antidepressant-like action have not been reported.