Open AccessAntihyperglycemic activity of Tectona grandis Linn. bark extract on alloxan induced diabetes in rats
Author(s) -
Sushil Kumar Varma,
Deepali Jaybhaye
Publication year - 2010
Publication title -
international journal of ayurveda research
Language(s) - English
Resource type - Journals
eISSN - 0974-925X
pISSN - 0974-7788
DOI - 10.4103/0974-7788.72488
Subject(s) - tectona , bark (sound) , traditional medicine , alloxan , herb , medicine , diabetes mellitus , biology , botany , medicinal herbs , endocrinology , ecology
Tectona Grandis Linn.(saag - tick wood), an indigenous medicinal plant, has a folk reputation among the Indian herbs as a hypoglycemic agent. The present study was carried out to evaluate the anti-hyperglycemic effect of T. grandis Linn. bark extract in control and alloxan-diabetic rats. Oral administration of the bark suspension of T. grandis (2.5 and 5 g/kg body wt.) for 30 days resulted in a significant reduction in blood glucose (from 250 ± 6.5 to 50 ± 2.5 mg/dL). Thus, the present study clearly shows that the T. grandis Linn. bark extract exerts anti-hyperglycemic activity.