Open AccessAnti-infective potential of hot-spring bacteria
Author(s) -
Pallavi Pednekar,
Ritika Jain,
Girish Mahajan
Publication year - 2011
Publication title -
journal of global infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 25
eISSN - 0974-8245
pISSN - 0974-777X
DOI - 10.4103/0974-777x.83529
Subject(s) - bacteria , biology , antibiotics , microorganism , agar diffusion test , antibiotic resistance , antibacterial activity , limiting , gram negative bacteria , microbiology and biotechnology , escherichia coli , biochemistry , genetics , mechanical engineering , gene , engineering
Antibiotic resistance currently spans most of the known classes of natural and synthetic antibiotics; limiting our options for treatment of infections and demanding discovery of new classes of antibiotics. Much effort is being directed towards developing new antibiotics to overcome this problem. Success in getting novel chemical entities from microbial sources depends essentially on novelty of its habitat. The diversity of geographical location decides the type of micro-flora. In the past various terrestrial and aqueous microorganisms have provided several novel bioactive secondary metabolites of pharmaceutical importance. Hot-springs have not been as extensively exploited as other terrestrial resources. However, perseverance with such microbes augment the probability of getting novel bioactive compounds.