Open AccessAntibiotic resistance pattern of uropathogens: An experience from north Indian cancer patient
Author(s) -
Nishat Hussain Ahmed,
Kausalya Raghuraman,
Frincy Khandelwal Baruah,
Rajesh K. Grover
Publication year - 2015
Publication title -
journal of global infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 25
eISSN - 0974-8245
pISSN - 0974-777X
DOI - 10.4103/0974-777x.161742
Subject(s) - nitrofurantoin , urinary system , medicine , enterococcus , urine , antibiotics , cephalosporin , antibiotic resistance , drug resistance , microbiology and biotechnology , biology
Empirical treatment of urinary tract infections (UTIs) can be made evidence based if it is governed by the resistance pattern of common uropathogens. A retrospective study was carried out at a tertiary care cancer institute to identify the common uropathogens and to know their resistance profile. 20.82% of the outpatients' urine samples (community-acquired urinary tract infection (CA-UTI)) and 24.83% of the indoor patients' urine samples (hospital-acquired urinary tract infection (HA-UTI)) grew uropathogens. Escherichia coli was the predominant pathogen both in CA-UTI (68%) and HA-UTI (45%) followed by Klebsiella spp and Enterococcus spp. High level of resistance to fluoroquinolones and third generation cephalosporins was noted. Nitrofurantoin was found to be a reliable oral drug for treatment of most of the uropathogens.