Open AccessComparative analysis of immunopathological features of lichen planopilaris and female patients with frontal fibrosing alopecia
Author(s) -
Emanuella Rd Cerqueira,
Neusa Yuriko Sakai Valente,
Mírian Nacagami Sotto,
Ricardo Romiti
Publication year - 2016
Publication title -
international journal of trichology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 22
eISSN - 0974-9241
pISSN - 0974-7753
DOI - 10.4103/0974-7753.203179
Subject(s) - scarring alopecia , medicine , pathology , scalp , biopsy , dermatology , cd68 , fibrosis , immunohistochemistry
Frontal fibrosing alopecia (FFA) is a disorder characterized by progressive cicatricial alopecia (CA). Its classification as a clinical variant of lichen planopilaris (LPP) or as a unique disorder is controversial. The presence of Langerhans cells within the bulge area and the sebaceous epithelium and the presence of lymphocytic infiltrate in this area in CA have led to a series of hypotheses, although limited, about their development. To our knowledge, scarce is the literature demonstrating immunoanalytical studies comparing both disorders.