Comparative analysis of immunopathological features of lichen planopilaris and female patients with frontal fibrosing alopecia | Zendy

EmanuellaRD Cerqueira | Zendy; Neusa Yuriko Sakai Valente | Zendy; Mírian Nacagami Sotto | Zendy; Ricardo Romiti | Zendy

Open Access

Comparative analysis of immunopathological features of lichen planopilaris and female patients with frontal fibrosing alopecia

Author(s) -

EmanuellaRD Cerqueira,

Neusa Yuriko Sakai Valente,

Mírian Nacagami Sotto,

Ricardo Romiti

Publication year - 2016

Publication title -

international journal of trichology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.494

H-Index - 22

eISSN - 0974-9241

pISSN - 0974-7753

DOI - 10.4103/0974-7753.203179

Subject(s) - scarring alopecia , medicine , pathology , scalp , biopsy , dermatology , cd68 , fibrosis , immunohistochemistry

Frontal fibrosing alopecia (FFA) is a disorder characterized by progressive cicatricial alopecia (CA). Its classification as a clinical variant of lichen planopilaris (LPP) or as a unique disorder is controversial. The presence of Langerhans cells within the bulge area and the sebaceous epithelium and the presence of lymphocytic infiltrate in this area in CA have led to a series of hypotheses, although limited, about their development. To our knowledge, scarce is the literature demonstrating immunoanalytical studies comparing both disorders.

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