Open AccessImmunohistochemistry Panel for Differential Diagnosis of Basal Cell Carcinoma and Trichoblastoma
Author(s) -
María Elisa Vega Memije,
Eduwiges Martínez Luna,
Oslei Paes de Almeida,
Adalberto Mosqueda Taylor,
Juan Carlos Cuevas-González
Publication year - 2014
Publication title -
international journal of trichology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 22
eISSN - 0974-9241
pISSN - 0974-7753
DOI - 10.4103/0974-7753.138583
Subject(s) - pathology , basal cell carcinoma , differential diagnosis , h&e stain , immunohistochemistry , malignancy , histopathology , neoplasm , staining , histology , epidermis (zoology) , basal (medicine) , carcinoma , anatomical pathology , biology , medicine , basal cell , anatomy , insulin , endocrinology
Basal cell carcinoma (BCC) is the most common malignant neoplasm in the skin and is considered to have a low degree of malignancy. BCC is invasive but rarely metastatic and originates in hair follicle-derived cells or interfollicular zones of the epidermis. Trichoblastoma (TB) is an infrequent benign skin neoplasm that differentiates toward follicular germinative cells. Both of these cutaneous lesions comprise nests of basaloid cells, and because the differential diagnosis is hard to obtain between them histologically due to their similarity, the correct diagnosis must be established.